About Our Company

MatTek Corporation, the manufacturer of Glass Bottom Culture Dishes, was founded in 1985 by two chemical engineering professors from MIT. In 1991 the company leveraged its core polymer surface modification technology into the emerging tissue engineering market.

MatTek Corporation is now a global industry leader in tissue engineering. The company manufactures human cell-based three-dimensional organotypic in vitro models for use in product development/efficacy, claims substantiation, safety assessment, and target organ research applications.

The current in vitro tissue product offering includes EpiDerm™, EpiDermFT™, MelanoDerm™, EpiOcular™, EpiAirway™., EpiOral™, and EpiVaginal™

EpiDerm, MatTek's first 3D human cell based in vitro model, was introduced in 1993 and became an immediate technical and commercial success. MatTek revolutionized the market for human cell-based in vitro models by:

• Reducing the cost of such models by 50-80%.
• Optimizing researchers' results by introducing published QC standards (concurrent positive and negative controls), assuring a level of reproducibility acceptable to industry and regulators.
• Increasing industry and regulator confidence in the performance of commercially available in vitro tissue models.

The creative use of non-animal (in vitro) testing was fueled by the powerful synergistic effect of lower (direct / indirect) costs and significantly improved product quality. MatTek dramatically reduced product cost and increased lab efficiency by consistently delivering high quality, reproducible, products. In turn, this has led to rapid acceptance and utilization of MatTek's in vitro products by a wide array of major international corporations.

EpiDerm's and EpiOcular's outstanding reproducibility directly led to impressive results in international multi-laboratory pre-validation and validation studies. Commercial companies are now empowered to achieve the desirable humane and sociopolitical goals of reducing the number animals used in research while simultaneously controlling costs and generating more relevant, species specific, reproducible data.

MatTek's human cell-based models are widely used in the United States, Europe and Japan. Commercial companies and academic researchers worldwide employ MatTek's models to explore an extremely wide variety of scientific challenges from apoptosis to zymography. MatTek's models are used for applications as diverse as skin irritation and basic research into cystic fibrosis.

An extensive list of references by academics and sector companies (pharmaceutical, chemical, cosmetic, household product) documents the broad problem solving capabilities of MatTek's products. This reference list is available on the MatTek web site.

New products under development include an immuno-competent skin model.